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Uganda steps up fight against Malaria with mass rollout of R21 Vaccine

A child being vaccinated the R21 Malaria Vaccine during the launch in Apac district.

Apac, Uganda:- The Government of Uganda, through the Ministry of Health, Wednesday officially launched a nationwide malaria vaccination campaign targeting children under five years old with the groundbreaking R21/Matrix-M vaccine.

This initiative marks the introduction of the R21/Matrix-M malaria vaccine into the country’s routine immunization schedule, targeting children aged six to 18 months. The vaccine becomes the 14th addition to Uganda’s list of immunizations against deadly diseases.

The launch ceremony, held on April 02, at Apac Boma Ground in Apac Municipality, was officiated by Prime Minister Rt. Hon. Robina Nabbanja, who reaffirmed the government’s commitment to safeguarding the health of Ugandan children.

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Health Minister, Dr. Jane Ruth Aceng Ocero noted that Apac District was intentionally selected for the launch due to its alarming rate of mosquito bites—the highest in the world.

“I appreciate the people of Lango and Apac District for their contributions, as well as our global partners; GAVI, WHO, UNICEF, and PATH, whose support has been instrumental in making this achievement possible,” Dr. Aceng said.

Nabbanja accompanied by various people as she arrives at Apac Boma Ground on Wednesday 2nd April 2025.

The R21/Matrix-M malaria vaccine becomes the 14th vaccine added to Uganda’s immunization program aimed at preventing deadly diseases. The Ministry of Health is aiming to vaccinate over one million children as part of this effort.

Dr. Daniel James Odongo, Apac District Health Officer, highlighted a disturbing increase in malaria cases, particularly among pregnant women. “In 2020, we registered 3,801 cases, and in 2024, the cases shot up to 4,343. This increase is largely due to mothers seeking assistance from traditional birth attendants, especially in Apoi and Akokoro Sub-counties,” he explained.

Local leaders, including Chegere Sub-County Councillor Sam Opira, called for intensified public awareness campaigns to combat misconceptions about the vaccine, which some communities attribute to witchcraft.

“Such beliefs have created many enemies in the community, as families of the deceased tend to blame neighbors for malaria deaths, claiming it is the result of witchcraft. We need more education and awareness campaigns to dispel these myths,” Opira emphasized.

Participants attending the event at Apac Boma Ground

Dr. Charles Olaro, Director General of Health Services, stressed that the vaccination campaign is part of a comprehensive strategy that includes mosquito-treated nets, indoor residual spraying, and timely diagnosis and treatment.

“Malaria vaccines are a powerful tool, but they should not replace other preventive measures. Use mosquito-treated nets, continue indoor residual spraying, and ensure timely diagnosis and treatment, which are available at our hospitals,” Dr. Olaro advised.

Linda Atim, a mother of two from Upper Center Cell, Agulu Division, expressed hope that the vaccine would lessen the burden of malaria.

“Sometimes malaria attacks our children, and when we go to the health facility, there are no drugs. This forces us to rely on private clinics, which many families cannot afford. With these vaccines, malaria cases will decrease,” Atim said.

Malaria: A Persistent Public Health Challenge

According to the 2024 Health Management Information System (HMS) report, approximately 32,900 people contract malaria daily in Uganda, disrupting lives and livelihoods. The average cost of treating a single case is approximately UGX 15,000, covering medication and transportation.

The introduction of the R21/Matrix-M vaccine provides new hope for combating malaria, particularly in high-risk districts like Apac. The government, along with global partners such as GAVI, WHO, UNICEF, and PATH, aims to eliminate malaria in Uganda by 2030.

With the campaign now underway, the Ministry of Health urges parents and caregivers to ensure their children complete the vaccination schedule for maximum protection.

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